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Antimicrobial, alcohol-free mouthwash containing cetylpyridinium chloride (CPC) may reduce the risk of premature birth in pregnant women who use it twice daily, according to a recent clinical trial sponsored by the Commonwealth of Pennsylvania and Proctor & Gamble Co. Trial results showed that pregnant women using mouthwash with the ammonium-based compound were less likely to experience premature birth than women who did not use the mouthwash, 6.1 percent and 21.9 percent, respectively. Statistics show that pregnancy hormones associated with an increased incidence of gum swelling and irritation may lead to premature birth. CPC is an antiseptic known to reduce this irritation and swelling by killing bacteria and microorganisms in the mouth.
AGD Impact, May 2011